| Catalog number: | bs-0015R-A488 |
|---|---|
| Price: | Ask price € |
| Supplier: | genways bulk |
| Product name: | IGF II Antibody, ALEXA FLUOR 488 |
| Quantity: | bulk |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, IGF II Polyclonal Antibody |
|---|---|
| Also known as: | Anti-IGF II PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | IGF II |
| Specificity: | This is a highly specific antibody against IGF II |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 20-70/180 |
| Subcellular location: | Secreted |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGF II |
| Gene ID Number: | 3481 |
| Swiss Prot: | P01344 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3, IGF-II is influenced by placental lactogen and may play a role in fetal development, In vitro, Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion, they are potent mitogens for cultured cells, The insulin-like growth factors possess growth-promoting activity |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | RBP4 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IGF II Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Description: | IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Gene target: | II |
| Short name: | IGF II Antibody |
| Technique: | antibodies against human proteins, antibodies for, igfs, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, IGF II (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 9191 |
| Gene: | POLR2D | More about : POLR2D |
| Long gene name: | RNA polymerase II subunit D |
| Synonyms gene name: | polymerase (RNA) II (DNA directed) polypeptide D |
| Synonyms name: | RNA polymerase II subunit hsRBP4 |
| Locus: | 2q14, 3 |
| Discovery year: | 1993-12-07 |
| GenBank acession: | U85510 |
| Entrez gene record: | 5433 |
| Pubmed identfication: | 9528765 |
| RefSeq identity: | NM_004805 |
| Classification: | RNA polymerase subunits |
| Havana BLAST/BLAT: | OTTHUMG00000131531 |
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