| Vial description: |
Dardarin |
| Category: |
primary antibody |
| Clonality: |
monoclonal |
| Raised in: |
Mouse |
| Clone: |
S231B-34 |
| Form: |
Purified |
| Reactivity: |
Rat, Human |
| Purity: |
purified |
| Molecular weight: |
in kDa |
| Source: |
mammalian |
| Activity: |
to be determined |
| Range: |
broad |
| Protein number: |
Q5S007 |
| Application: |
Immunocytochemistry/Immunofluorescence, Western Blot |
| Storage: |
Avoid freeze/thaw cycles, Upon delivery aliquot and store at -20°, C, C for one year, Shipped at 4° |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by acr they should be stored frozen at - 24° |
| Gene target: |
PARK8 / LRRK2 (841-960) |
| Short name: |
anti-PARK8 / LRRK2 (841-960) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-PARK8 / leucine-rich repeat kinase 2 (841-960) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, LRRK2 and IDBG-27257 and ENSG00000188906 and 120892, LRRK2 and IDBG-633456 and ENSBTAG00000016260 and 535652, Lrrk2 and IDBG-175625 and ENSMUSG00000036273 and 66725, glutamatergic and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060159 and regulation of dopamine receptor signaling pathway and biological process this GO :0060161 and positive regulation of dopamine receptor signaling pathway and biological process this GO :0061001 and regulation of dendritic spine morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070997 and neuron death and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :1901214 and regulation of neuron death and biological process this GO :1902692 and regulation of neuroblast proliferation and biological process this GO :1902803 and regulation of synaptic vesicle transport and biological process this GO :1902823 and negative regulation of late endosome to lysosome transport and biological process this GO :1903125 and negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation and biological process this GO :2000172 and regulation of branching morphogenesis of a nerve and biological process this GO :2000300 and regulation of synaptic vesicle exocytosis and biological process, this GO :0000149 and SNARE binding and molecular function this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003779 and actin binding and molecular function this GO :0003924 and GTPase activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004708 and MAP kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006914 and autophagy and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007528 and neuromuscular junction development and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008340 and determination of adult lifespan and biological process this GO :0010508 and positive regulation of autophagy and biological process this GO :0010738 and regulation of protein kinase A signaling and biological process this GO :0014041 and regulation of neuron maturation and biological process this GO :0015031 and protein transport and biological process this GO :0015631 and tubulin binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016234 and inclusion body and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, this GO :0000149 : SNARE binding, this GO :0000149 : SNARE binding and also this GO :0001948 : glycoprotein binding and also this GO :0003779 : actin binding and also this GO :0003924 : GTPase activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004708 : MAP kinase kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004857 : enzyme inhibitor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0015631 : tubulin binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0001948 : glycoprotein binding, this GO :0003779 : actin binding, this GO :0003924 : GTPase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004708 : MAP kinase kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004857 : enzyme inhibitor activity, this GO :0005096 : GTPase activator activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0015631 : tubulin binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0017048 : Rho GTPase binding, this GO :0017075 : syntaxin-1 binding, this GO :0030276 : clathrin binding, this GO :0034211 : GTP-dependent protein kinase activity, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0044325 : ion channel binding, this GO :0051018 : protein kinase A binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017048 : Rho GTPase binding and also this GO :0017075 : syntaxin-1 binding and also this GO :0030276 : clathrin binding and also this GO :0034211 : GTP-dependent protein kinase activity and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0044325 : ion channel binding and also this GO :0051018 : protein kinase A binding, transferring phosphorus-containing groups and molecular function this GO :0017048 and Rho GTPase binding and molecular function this GO :0017075 and syntaxin-1 binding and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0021772 and olfactory bulb development and biological process this GO :0022028 and tangential migration from the subventricular zone to the olfactory bulb and biological process this GO :0030276 and clathrin binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031966 and mitochondrial membrane and cellular component this GO :0032091 and negative regulation of protein binding and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0032473 and external side of mitochondrial outer membrane and cellular component this GO :0032839 and dendrite cytoplasm and cellular component this GO :0034211 and GTP-dependent protein kinase activity and molecular function this GO :0034260 and negative regulation of GTPase activity and biological process this GO :0034613 and cellular protein localization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035564 and regulation of kidney size and biological process this GO :0035640 and exploration behavior and biological process this GO :0035641 and locomotory exploration behavior and biological process this GO :0040012 and regulation of locomotion and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043068 and positive regulation of programmed cell death and biological process this GO :0043204 and perikaryon and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045202 and synapse and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048312 and intracellular distribution of mitochondria and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0051018 and protein kinase A binding and molecular function this GO :0051900 and regulation of mitochondrial depolarization and biological process this GO :0051966 and regulation of synaptic transmission, leucine-rich repeat kinase 2 |
| Identity: |
18618 |
| Gene: |
LRRK2 |
More about : LRRK2 |
| Long gene name: |
leucine rich repeat kinase 2 |
| Synonyms gene: |
PARK8 |
| Synonyms gene name: |
Parkinson disease (autosomal dominant) 8 |
| Synonyms: |
ROCO2 DKFZp434H2111 FLJ45829 RIPK7 |
| Locus: |
12q12 |
| Discovery year: |
2004-10-22 |
| GenBank acession: |
AK026776 |
| Entrez gene record: |
120892 |
| Pubmed identfication: |
15541308 |
| RefSeq identity: |
XM_058513 |
| Classification: |
Parkinson disease associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000059742 |
| Locus Specific Databases: |
Parkinson', s disease Mutation Database |