| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Interferon alpha/beta Receptor 1 is produced by our Mammalian expression system and the target gene encoding Lys28-Lys436 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
18 kD, 48 |
| UniProt number: |
P17181 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
150 mM sodium chloride, pH 7, 2, 2 um filtered solution of 20 mM PB, Lyophilized from a 0 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Avoid mixing using vortex or pipettes, Dissolve the protein in ddH2O, In order to retain the quality and the affinity of the product unchanged, It is not recommended to dilute the product to less than 100 &mu, avoid cycles of freezing and thawing, please, The vials should be centrifuged before it is opened, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
KNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKLDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
&beta, IFNAR1 (C-6His), Receptor 1, Interferon &alpha |
| Short name: |
&beta, IFNAR1 (C-6His), Receptor 1, Recombinant Interferon &alpha |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans |
| Alternative name: |
&beta, Receptor 1, b and omega) receptor 1 (C-6His), interferon (a, sapiens Interferon &alpha, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
AVP and IFN-alpha-REC and IFNAR and IFNBR and IFRC, IFNAR1 and IDBG-2095 and ENSG00000142166 and 3454, IFNAR1 and IDBG-629846 and ENSBTAG00000021819 and 282257, Ifnar1 and IDBG-176038 and ENSMUSG00000022967 and 15975, Plasma membranes, beta and omega) receptor 1, protein binding, this GO :0004904 and interferon receptor activity and molecular function this GO :0004905 and type I interferon receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, this GO :0004904 : interferon receptor activity, this GO :0004904 : interferon receptor activity and also this GO :0004905 : type I interferon receptor activity and also this GO :0005515 : protein binding, this GO :0004905 : type I interferon receptor activity, this GO :0005515 : protein binding, interferon (alpha |
| Identity: |
5432 |
| Gene: |
IFNAR1 |
More about : IFNAR1 |
| Long gene name: |
interferon alpha and beta receptor subunit 1 |
| Synonyms gene: |
IFNAR |
| Synonyms gene name: |
beta and omega) receptor 1 , interferon (alpha |
| Synonyms: |
IFRC |
| Locus: |
21q22, 11 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
3454 |
| Pubmed identfication: |
8181059 |
| Classification: |
Interferon receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000065126 |