| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SDHA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:25, Western blot: 1:1000 |
| Notes: |
Titration of the SDHA antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This SDHA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P31040 |
| Purity: |
Antigen affinity |
| Description: |
Can act as a tumor suppressor, Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) |
| Immunogen: |
A portion of amino acids 577-605 from the human protein was used as the immunogen for this SDHA antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SDHA antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SDHA |
| Short name: |
SDHA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SDHA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10680 |
| Gene: |
SDHA |
More about : SDHA |
| Long gene name: |
succinate dehydrogenase complex flavoprotein subunit A |
| Synonyms gene: |
SDH2 |
| Synonyms gene name: |
flavoprotein (Fp) , flavoprotein (Fp) succinate dehydrogenase complex subunit A, subunit A, succinate dehydrogenase complex |
| Synonyms: |
FP SDHF |
| Synonyms name: |
succinate dehydrogenase [ubiquinone] flavoprotein subunit flavoprotein subunit of complex II |
| Locus: |
5p15, 33 |
| Discovery year: |
1995-10-24 |
| GenBank acession: |
BC001380 |
| Entrez gene record: |
6389 |
| Pubmed identfication: |
7798181 |
| RefSeq identity: |
NM_004168 |
| Classification: |
Mitochondrial complex II: succinate dehydrogenase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000090275 |
| Locus Specific Databases: |
SDHA @ LOVD TCA Cycle Gene Mutation Database LRG_315 |