| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MARCO |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the MARCO antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This MARCO antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UEW3 |
| Purity: |
Antigen affinity |
| Description: |
C-terminal, In addition to short cytoplasmic and transmembrane domains, The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains, extracellular collagenous domain, scavenger receptor cysteine-rich (SRCR) domain, there is an extracellular spacer domain and a long, MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system |
| Immunogen: |
A portion of amino acids 13-40 from the human protein was used as the immunogen for this MARCO antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MARCO antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MARCO |
| Short name: |
MARCO Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
macrophage receptor including collagenous structure (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
MARCO and IDBG-642407 and ENSBTAG00000018473 and, MARCO and IDBG-67847 and ENSG00000019169 and 8685, Marco and IDBG-188086 and ENSMUSG00000026390 and 17167, Plasma membranes, SCARA2, signaling pattern recognition receptor activity, this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005581 and collagen trimer and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005044 : scavenger receptor activity and also this GO :0008329 : signaling pattern recognition receptor activity, this GO :0005044 : scavenger receptor activity, this GO :0008329 : signaling pattern recognition receptor activity, macrophage receptor with collagenous structure |
| Identity: |
6895 |
| Gene: |
MARCO |
More about : MARCO |
| Long gene name: |
macrophage receptor with collagenous structure |
| Synonyms: |
SCARA2 |
| Synonyms name: |
member 2 , scavenger receptor class A |
| Locus: |
2q14, 2 |
| Discovery year: |
1998-11-26 |
| GenBank acession: |
AF035819 |
| Entrez gene record: |
8685 |
| Pubmed identfication: |
9468508 7867067 10331948 |
| RefSeq identity: |
NM_006770 |
| Classification: |
Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131400 |