| Alternative name 1: |
C-terminal domain, Clone: ED31, FITC, Rat Mab anti-, Mouse MARCO (Macrophage Receptor with Collagenous Structure) |
| Alternative name 2: |
C-terminal domain, Clone: ED31, FITC, Rat Mab antibody-, Mouse MARCO (Macrophage Receptor with Collagenous Structure) |
| Alternative name 3: |
C-terminal domain, Clone: ED31, FITC, Rattus norvegicus Mab antibody-, Mus musculus MARCO (Macrophage Receptor with Collagenous Structure) |
| Alternative name 4: |
anti- MARCO Macrophage Receptor with Collagenous Structure C-terminal domain Clone: ED31 |
| Alternative name 5: |
MARCO Macrophage Receptor with Collagenous Structure C-terminal domain Clone: ED31 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, accurate-monoclonals FITC is highly sensitive to pH extremes, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This accurate-monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
ED31, Monoclonal, MARCO (Macrophage Receptor with Collagenous Structure) domain |
| Short name: |
Clone: ED31, Mouse Monoclonal antibody- FITC, Mouse MARCO (Macrophage Receptor with Collagenous Structure) C-terminal domain |
| Technique: |
Fluorescein, Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Label: |
FITC |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
C-terminal domain, Rat Mouse monoclonal (Antibody to)-, clonality: ED31, fluorecein, Mouse macrophage receptor including collagenous structure (Macrophage Receptor including Collagenous Structure) |
| Alternative technique: |
murine |
| Alternative to gene target: |
MARCO and IDBG-642407 and ENSBTAG00000018473 and, MARCO and IDBG-67847 and ENSG00000019169 and 8685, Marco and IDBG-188086 and ENSMUSG00000026390 and 17167, Plasma membranes, SCARA2, signaling pattern recognition receptor activity, this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005581 and collagen trimer and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005044 : scavenger receptor activity and also this GO :0008329 : signaling pattern recognition receptor activity, this GO :0005044 : scavenger receptor activity, this GO :0008329 : signaling pattern recognition receptor activity, macrophage receptor with collagenous structure |
| Identity: |
6895 |
| Gene: |
MARCO |
More about : MARCO |
| Long gene name: |
macrophage receptor with collagenous structure |
| Synonyms: |
SCARA2 |
| Synonyms name: |
member 2 , scavenger receptor class A |
| Locus: |
2q14, 2 |
| Discovery year: |
1998-11-26 |
| GenBank acession: |
AF035819 |
| Entrez gene record: |
8685 |
| Pubmed identfication: |
9468508 7867067 10331948 |
| RefSeq identity: |
NM_006770 |
| Classification: |
Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131400 |