| Also known as: |
MARCO |
| Other names: |
Macrophage receptor MARCO, Macrophage receptor with collagenous structure, macrophage receptor MARCO, macrophage receptor with collagenous structure, macrophage receptor MARCO |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MARCO |
| Other gene names: |
AI323439, Ly112, Marco, N/A, Scara2, Marco |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
ED31 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
ED31 binds to the C-terminal cysteine rich domain of MARCO, Liver Kupffer cells) during infection or LPS treatment, MARCO is expressed by distinct populations of macrophages in the spleen and lymph nodes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and has been shown to block ligand binding, but is rapidly induced on macrophages in other tissues (e, which is a member of the class A scavenger receptor family, MARCO This item recognises the murine cell surface antigen designated MARCO (Macrophage receptor with collagenous structure), g |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
MARCO |
| Short name: |
RAT ANTI MOUSE MARCO Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE macrophage receptor including collagenous structure (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
MARCO and IDBG-642407 and ENSBTAG00000018473 and, MARCO and IDBG-67847 and ENSG00000019169 and 8685, Marco and IDBG-188086 and ENSMUSG00000026390 and 17167, Plasma membranes, SCARA2, signaling pattern recognition receptor activity, this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005581 and collagen trimer and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005044 : scavenger receptor activity and also this GO :0008329 : signaling pattern recognition receptor activity, this GO :0005044 : scavenger receptor activity, this GO :0008329 : signaling pattern recognition receptor activity, macrophage receptor with collagenous structure |
| Identity: |
6895 |
| Gene: |
MARCO |
More about : MARCO |
| Long gene name: |
macrophage receptor with collagenous structure |
| Synonyms: |
SCARA2 |
| Synonyms name: |
member 2 , scavenger receptor class A |
| Locus: |
2q14, 2 |
| Discovery year: |
1998-11-26 |
| GenBank acession: |
AF035819 |
| Entrez gene record: |
8685 |
| Pubmed identfication: |
9468508 7867067 10331948 |
| RefSeq identity: |
NM_006770 |
| Classification: |
Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131400 |