| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BCL6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB, IHC |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the BCL6 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BCL6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P41182 |
| Purity: |
Antigen affinity |
| Description: |
This protein acts as a sequence-specific repressor of transcription, This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells, BCL6 is a zinc finger transcription factor and contains an N-terminal POZ domain |
| Immunogen: |
A portion of amino acids 519-547 from the human protein was used as the immunogen for this BCL6 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BCL6 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BCL6 |
| Short name: |
BCL6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B-cell CLL/lymphoma 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BCL5 and BCL6A and LAZ3 and ZBTB27 and ZNF51, BCL6 and IDBG-634562 and ENSBTAG00000001511 and 539020, BCL6 and IDBG-69349 and ENSG00000113916 and 604, Bcl6 and IDBG-149890 and ENSMUSG00000022508 and 12053, DNA-templated and biological process this GO :0006954 and inflammatory response and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008104 and protein localization and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031490 and chromatin DNA binding and molecular function this GO :0032319 and regulation of Rho GTPase activity and biological process this GO :0032764 and negative regulation of mast cell cytokine production and biological process this GO :0035024 and negative regulation of Rho protein signal transduction and biological process this GO :0042092 and type 2 immune response and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043380 and regulation of memory T cell differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045629 and negative regulation of T-helper 2 cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048294 and negative regulation of isotype switching to IgE isotypes and biological process this GO :0048821 and erythrocyte development and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051272 and positive regulation of cellular component movement and biological process, metal ion binding, nuclei, this GO :0000060 and protein import into nucleus, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0031490 : chromatin DNA binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0031490 : chromatin DNA binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, translocation and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001227 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0002467 and germinal center formation and biological process this GO :0002634 and regulation of germinal center formation and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0002903 and negative regulation of B cell apoptotic process and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005657 and replication fork and cellular component this GO :0006351 and transcription, B-cell CLL/lymphoma 6 |
| Identity: |
1001 |
| Gene: |
BCL6 |
More about : BCL6 |
| Long gene name: |
B-cell CLL/lymphoma 6 |
| Synonyms gene: |
ZNF51 |
| Synonyms gene name: |
zinc finger protein 51 |
| Synonyms: |
ZBTB27 LAZ3 BCL5 BCL6A |
| Locus: |
3q27, 3 |
| Discovery year: |
1993-04-12 |
| Entrez gene record: |
604 |
| RefSeq identity: |
NM_001706 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000156441 |