| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Anti-ATG5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:25, Western blot: 1:1000 |
| Notes: |
Titration of the anti-ATG5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This anti-ATG5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H1Y0 |
| Purity: |
Antigen affinity |
| Description: |
APG5, APG5 may also play an important role in the apoptotic process, Its expression is a relatively late event in the apoptotic process, The conjugate detaches from the membrane immediately before or after autophagosome formation is completed, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation, occurring downstream of caspase activity, possibly within the modified cytoskeleton, required for autophagy, Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells |
| Immunogen: |
A portion of amino acids 209-238 from the human protein was used as the immunogen for this anti-ATG5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-ATG5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ATG5 |
| Short name: |
Anti-ATG5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-autophagy related 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APG5 and APG5-LIKE and APG5L and ASP and hAPG5, ATG5 and IDBG-631895 and ENSBTAG00000005400 and 532686, ATG5 and IDBG-94856 and ENSG00000057663 and 9474, Atg5 and IDBG-148568 and ENSMUSG00000038160 and 11793, Plasma membranes, protein binding, this GO :0000045 and autophagic vacuole assembly and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002739 and regulation of cytokine secretion involved in immune response and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005776 and autophagic vacuole and cellular component this GO :0005930 and axoneme and cellular component this GO :0006914 and autophagy and biological process this GO :0006915 and apoptotic process and biological process this GO :0009620 and response to fungus and biological process this GO :0016020 and membrane and cellular component this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0034045 and pre-autopha this GO somal structure membrane and cellular component this GO :0039689 and negative stranded viral RNA replication and biological process this GO :0042311 and vasodilation and biological process this GO :0042493 and response to drug and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0045087 and innate immune response and biological process this GO :0048840 and otolith development and biological process this GO :0055015 and ventricular cardiac muscle cell development and biological process this GO :0060047 and heart contraction and biological process this GO :1902017 and regulation of cilium assembly and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, autophagy related 5 |
| Identity: |
589 |
| Gene: |
ATG5 |
More about : ATG5 |
| Long gene name: |
autophagy related 5 |
| Synonyms gene: |
APG5L |
| Synonyms gene name: |
APG5 (autophagy 5, S, cerevisiae) , cerevisiae) ATG5 autophagy related 5 homolog (S, cerevisiae)-like APG5 autophagy 5-like (S |
| Synonyms: |
ASP APG5 hAPG5 |
| Locus: |
6q21 |
| Discovery year: |
1999-09-16 |
| GenBank acession: |
Y11588 |
| Entrez gene record: |
9474 |
| Pubmed identfication: |
9563500 11349150 15778222 |
| RefSeq identity: |
NM_004849 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000016193 |