IRF9 Antibody

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Catalog number: F41756-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: IRF9 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1ml 263€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: IRF9
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IF, IHC, WB
Recommended dilutions: IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the IRF9 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This IRF9 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q00978
Purity: Antigen affinity
Description: Following type I IFN binding to cell surface receptors, ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, Jak kinases (TYK2 and JAK1) are activated, The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, leading to tyrosine phosphorylation of STAT1 and STAT2, that enters the nucleus, which drive the cell in an antiviral state, IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta)
Immunogen: A portion of amino acids 75-104 from the human protein was used as the immunogen for this IRF9 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IRF9 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: IRF9
Short name: IRF9 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: interferon regulatory factor 9 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, IRF9 and IDBG-236583 and ENSG00000213928 and 10379, Irf9 and IDBG-164579 and ENSMUSG00000002325 and 16391, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, 92462 and IDBG-645738 and ENSBTAG00000005816 and 509855, interferon regulatory factor 9
Identity: 6131
Gene: IRF9 | More about : IRF9
Long gene name: interferon regulatory factor 9
Synonyms gene: ISGF3G
Synonyms gene name: gamma (48kD) interferon-stimulated transcription factor 3, gamma 48kDa , interferon-stimulated transcription factor 3
Locus: 14q12
Discovery year: 1999-06-21
GenBank acession: M87503
Entrez gene record: 10379
Pubmed identfication: 1630447 10199920
Havana BLAST/BLAT: OTTHUMG00000028799

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