| Long name: |
Biotin Conjugated, IRF9 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IRF9 |
| Specificity: |
This is a highly specific antibody against IRF9 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-145/393 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human IRF9 |
| Gene ID number: |
10379 |
| Swiss Prot: |
Q00978 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Following type I IFN binding to cell surface receptors, IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2, that enters the nucleus, which drive the cell in an antiviral state, Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IRF9 Conjugated |
| Short name: |
IRF9 Antibody Conjugated |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, interferon regulatory factor 9 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, IRF9 and IDBG-236583 and ENSG00000213928 and 10379, Irf9 and IDBG-164579 and ENSMUSG00000002325 and 16391, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, 92462 and IDBG-645738 and ENSBTAG00000005816 and 509855, interferon regulatory factor 9 |
| Identity: |
6131 |
| Gene: |
IRF9 |
More about : IRF9 |
| Long gene name: |
interferon regulatory factor 9 |
| Synonyms gene: |
ISGF3G |
| Synonyms gene name: |
gamma (48kD) interferon-stimulated transcription factor 3, gamma 48kDa , interferon-stimulated transcription factor 3 |
| Locus: |
14q12 |
| Discovery year: |
1999-06-21 |
| GenBank acession: |
M87503 |
| Entrez gene record: |
10379 |
| Pubmed identfication: |
1630447 10199920 |
| Havana BLAST/BLAT: |
OTTHUMG00000028799 |