| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IRF9 |
| Specificity: |
This antibody reacts specifically with IRF9 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IRF9 |
| Gene ID: |
10379 |
| Swiss Prot: |
Q00978 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Following type I IFN binding to cell surface receptors, IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2, that enters the nucleus, which drive the cell in an antiviral state, Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
IRF9 Polyclonal Antibody |
| Other name: |
Anti-IRF9 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IRF9 |
| Short name: |
Anti-IRF9 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-interferon regulatory factor 9 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, IRF9 and IDBG-236583 and ENSG00000213928 and 10379, Irf9 and IDBG-164579 and ENSMUSG00000002325 and 16391, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, 92462 and IDBG-645738 and ENSBTAG00000005816 and 509855, interferon regulatory factor 9 |
| Identity: |
6131 |
| Gene: |
IRF9 |
More about : IRF9 |
| Long gene name: |
interferon regulatory factor 9 |
| Synonyms gene: |
ISGF3G |
| Synonyms gene name: |
gamma (48kD) interferon-stimulated transcription factor 3, gamma 48kDa , interferon-stimulated transcription factor 3 |
| Locus: |
14q12 |
| Discovery year: |
1999-06-21 |
| GenBank acession: |
M87503 |
| Entrez gene record: |
10379 |
| Pubmed identfication: |
1630447 10199920 |
| Havana BLAST/BLAT: |
OTTHUMG00000028799 |