TRPM8 Antibody

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Catalog number: F41678-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: TRPM8 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 406€ 0.1ml 263€ 0.4 ml 406€ 1 vial 532€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: TRPM8
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IF, WB, IHC
Recommended dilutions: IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the TRPM8 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This TRPM8 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q7Z2W7
Purity: Purified
Description: Activated by icilin, Activated upon depolarization, Involved in menthol sensation, Permeable for monovalent cations sodium, Temperature sensing is tightly linked to voltage-dependent gating, Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing, The chemical agonists menthol functions as a gating modifier, and cesium and divalent cation calcium, by being activated by cold temperature below 25 degrees Celsius, changes in temperature resulting in graded shifts of its voltage-dependent activation curves, cold and modulation of intracellular pH, eucalyptol, menthol, potassium, shifting activation curves towards physiological membrane potentials, Receptor-activated non-selective cation channel involved in detection of sensations such as coolness
Immunogen: A portion of amino acids 263-292 from the human protein was used as the immunogen for this TRPM8 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPM8 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: TRPM8
Short name: TRPM8 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: TRPM8 (Antibody to)
Alternative technique: antibodies
Identity: 17961
Gene: TRPM8 | More about : TRPM8
Long gene name: transient receptor potential cation channel subfamily M member 8
Synonyms gene name: member 8 , subfamily M, transient receptor potential cation channel
Locus: 2q37, 1
Discovery year: 2002-01-11
GenBank acession: AC005538
Entrez gene record: 79054
Pubmed identfication: 16382100
RefSeq identity: NM_024080
Classification: Transient receptor potential cation channels
Havana BLAST/BLAT: OTTHUMG00000059129

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