| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPM8 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the TRPM8 antibody should be determined by the researcher |
| Intented use: |
This TRPM8 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q7Z2W7 |
| Purity: |
Antigen affinity |
| Description: |
TRPM8 is an ion channel, The TRPM8 protein is expressed in sensory neurons, The signal is conducted from primary afferents (type C- and A-delta) eventually leading to the sensation of cold and cold pain, also known as the cold and menthol receptor 1 (CMR1), and it is activated by cold temperatures and cooling agents, is a protein that in humans is encoded by the TRPM8 gene, such as menthol and icilin whereas WS-12 and CPS-369 are the most selective agonist of TRPM8, upon activation it allows the entry of Na+ (sodium) and Ca2+ (calcium) ions to the cell that leads to depolarization and the generation of an action potential, Transient receptor potential cation channel subfamily M member 8 |
| Immunogen: |
Amino acids NTKANDTSEEMRHRFRQLDTKLNDLKGLLKEIANKIK of human TRPM8 were used as the immunogen for the TRPM8 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRPM8 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPM8 |
| Short name: |
TRPM8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPM8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17961 |
| Gene: |
TRPM8 |
More about : TRPM8 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 8 |
| Synonyms gene name: |
member 8 , subfamily M, transient receptor potential cation channel |
| Locus: |
2q37, 1 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AC005538 |
| Entrez gene record: |
79054 |
| Pubmed identfication: |
16382100 |
| RefSeq identity: |
NM_024080 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000059129 |