| Gene info: |
<, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan interglobular domain, Activates progelatinase A by cleavage of the propeptide at 37-Asn-|-Leu-38, May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface, Other bonds hydrolyzed include 35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-342, <, /b>, /b>, : Endopeptidase activity, : Seems to specifically activate progelatinase A, CATALYTIC ACTIVITY<, FUNCTION<, b>, b> |
| Gene names: |
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, Matrix metalloproteinase14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, WNCHRS, Matrix metalloproteinase-14MMP-14 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
126-230 |
| Immuno application: |
Western Blot |
| Antibody advice: |
Matrix metalloproteinase-14 antibody can be used for the detection of Matrix metalloproteinase-14 by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, MMP14 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Bovine, Rat, Human |
| Omim nr: |
4826834 |
| Ncbi nr: |
1, NP_004986 |
| KDa: |
65, 9 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
4323 |
| GENE symbol: |
MMP14 |
| Antigene name: |
matrix metallopeptidase 14 (membrane-inserted) |
| Source: |
Homo sapiens |
| Protein nr: |
P50281 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
MMP14 |
| Short name: |
anti-MMP14 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-MMP14 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7160 |
| Gene: |
MMP14 |
More about : MMP14 |
| Long gene name: |
matrix metallopeptidase 14 |
| Synonyms gene name: |
matrix metalloproteinase 14 (membrane-inserted) matrix metallopeptidase 14 (membrane-inserted) |
| Synonyms: |
MT1-MMP |
| Synonyms name: |
membrane type 1 metalloprotease |
| Locus: |
14q11, 2 |
| Discovery year: |
1994-11-20 |
| Entrez gene record: |
4323 |
| Pubmed identfication: |
8015608 |
| RefSeq identity: |
NM_004995 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000028704 |