| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MMP14 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MMP14 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P50281 |
| Purity: |
Antigen affinity |
| Description: |
It acts as a positive regulator of cell growth and migration via activation of MMP15, Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, The protein encoded by this gene is a member of the membrane-type MMP subfamily, This gene is mapped to 14q11, This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7, also called MT-MMP 1, and tissue remodeling, as well as in disease processes, is an enzyme that in humans is encoded by the MMP14 gene, reproduction, such as arthritis and metastasis, such as embryonic development, 2, Matrix metalloproteinase-14 |
| Immunogen: |
An amino acid sequence from the C-terminus of human Matrix metalloproteinase-14 (TPRRLLYCQRSLLDKV) was used as the immunogen for this MMP14 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP14 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MMP14 |
| Short name: |
MMP14 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MMP14 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7160 |
| Gene: |
MMP14 |
More about : MMP14 |
| Long gene name: |
matrix metallopeptidase 14 |
| Synonyms gene name: |
matrix metalloproteinase 14 (membrane-inserted) matrix metallopeptidase 14 (membrane-inserted) |
| Synonyms: |
MT1-MMP |
| Synonyms name: |
membrane type 1 metalloprotease |
| Locus: |
14q11, 2 |
| Discovery year: |
1994-11-20 |
| Entrez gene record: |
4323 |
| Pubmed identfication: |
8015608 |
| RefSeq identity: |
NM_004995 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000028704 |