| Long name: |
1) Monoclonal Antibody, 5, 10, MMP14 (133CT15 |
| Also known as: |
1) Monoclonal Antibody, 5, 10, MMP14 (133CT15 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MMP14 |
| Specificity: |
This is a highly specific antibody against MMP14 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1, 5, 10, 133CT15 |
| Source: |
This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14 |
| Gene ID number: |
4323 |
| Swiss Prot: |
P50281 |
| Tested Applications: |
IF, WB |
| Recommended dilutions: |
WB(1:200-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a positive regulator of cell growth and migration via activation of MMP15, Involved in the formation of the fibrovascular tissues in association with pro-MMP2, May be involved in actin cytoskeleton reorganization by cleaving PTK7, May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface, Seems to specifically activate progelatinase A |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MMP-X1, MMP14, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, WNCHRS, MMP-14 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
1) Monoclonal, 5, 10, MMP14 (133CT15 |
| Short name: |
1) Monoclonal Antibody, 5, 10, MMP14 (133CT15 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
1) monoclonal (Antibody to), 5, 10, MMP14 (133CT15 |
| Alternative technique: |
antibodies |
| Identity: |
7160 |
| Gene: |
MMP14 |
More about : MMP14 |
| Long gene name: |
matrix metallopeptidase 14 |
| Synonyms gene name: |
matrix metalloproteinase 14 (membrane-inserted) matrix metallopeptidase 14 (membrane-inserted) |
| Synonyms: |
MT1-MMP |
| Synonyms name: |
membrane type 1 metalloprotease |
| Locus: |
14q11, 2 |
| Discovery year: |
1994-11-20 |
| Entrez gene record: |
4323 |
| Pubmed identfication: |
8015608 |
| RefSeq identity: |
NM_004995 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000028704 |