| Gene info: |
Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits, The NMDAR plays an essential role in memory, The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ, The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned, Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR), epilepsy and ischemic neuronal cell death, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer&rsquo, The ion channels activated by glutamate are typically divided into two classes, s |
| Gene names: |
GluN2C, N-methyl D-aspartate receptor subtype 2C, NR2C |
| Antibodie's label: |
unlabelled serum |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Antigen: |
NMDA NR2C polyclonal antibody was made against an N-terminal fusion protein of the NR2C subunit of the NMDAR |
| Immuno application: |
immuno precipitation, Western Blot |
| Antibody advice: |
Antibody dilutions and tissue load should be based on tissue type and expected expression level of the protein, Applications include Dot Blots (DB), DB and WB, Human, Immunohistochemistry (IHC), Immunolabeling blocked by preadsorption of antibody with the N-terminal fusion protein of the NMDAR2C that was used to generate the antibody, Immunoprecipitation (IP) and Western Blots (WB), Initial recommended range of dilutions: 1:500 to 1:2000, When internally tested under ideal conditions the working dilutions were 1:1000 for IHC, and it labels the 180k NR2A and NR2B subunits of the NMDAR, and rat have 100% amino acid sequence identity with the antigen used to raise the antibody, mouse, NMDA NR2C Subunit antibody labels the 140k NR2C band in Western blots of cerebellum |
| Keep at: |
After reconstitution in 50 &, Ambient shipment is suitable for both international and domestic, the antibody should be aliquot and stored at -20 grades C and is stable at -20 grades C for at least 1 year, #956, NMDA NR2C Subunit antibody can be stored at -20 grades C, l PBS |
| Works with: |
Rat, Human |
| Omim nr: |
548374 |
| Ncbi nr: |
Q00961 |
| Vial with antibody: |
in solution |
| NCBI GENE nr: |
24411 |
| GENE symbol: |
Grin2c |
| Antigene name: |
N-methyl D-aspartate 2C, ionotropic, glutamate receptor |
| Source: |
Rattus norvegicus |
| Protein nr: |
Q00961 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
NMDA NR2C |
| Short name: |
anti-NMDA NR2C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-NMDA NR2C (Antibody to) |
| Alternative technique: |
antibodies |