| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TMEM2L |
| Specificity: |
This antibody reacts specifically with TMEM2L |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TMEM2L |
| Gene ID: |
57214 |
| Swiss Prot: |
Q8WUJ3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds to hyaluronic acid, Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, In collaboration with HSPA5/BIP, Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium, May be involved in hearing, Positively regulates epithelial-mesenchymal transition (EMT), a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes, and hence tumor cell growth, invasion and cancer dissemination, promotes cancer cell migration in a calcium and PKC-dependent manner, Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IR2155535 TMEM2L HYBID |
| Also known as: |
TMEM2L Polyclonal Antibody |
| Other name: |
Anti-TMEM2L Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TMEM2L |
| Short name: |
Anti-TMEM2L (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TMEM2L (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
29213 |
| Gene: |
CEMIP |
More about : CEMIP |
| Long gene name: |
cell migration inducing hyaluronan binding protein |
| Synonyms gene: |
KIAA1199 |
| Synonyms gene name: |
KIAA1199 cell migration inducing protein, hyaluronan binding |
| Synonyms name: |
hyaluronan-binding protein involved in hyaluronan depolymerization |
| Locus: |
15q25, 1 |
| Discovery year: |
2004-06-29 |
| GenBank acession: |
BC020256 |
| Entrez gene record: |
57214 |
| Pubmed identfication: |
14577002 16157444 24573670 |
| RefSeq identity: |
NM_018689 |
| Havana BLAST/BLAT: |
OTTHUMG00000144184 |