| Long name: |
TMEM2L Primary Polyclonal Antibody |
| Also known as: |
TMEM2L PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TMEM2L |
| Specificity: |
This is a highly specific antibody against TMEM2L |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-177/1361 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM2L |
| Gene ID number: |
57214 |
| Swiss Prot: |
Q8WUJ3 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds to hyaluronic acid, Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, In collaboration with HSPA5/BIP, Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium, May be involved in hearing, Positively regulates epithelial-mesenchymal transition (EMT), a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes, and hence tumor cell growth, invasion and cancer dissemination, promotes cancer cell migration in a calcium and PKC-dependent manner, Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CEMIP, Cell migration-inducing and hyaluronan-binding protein, KIAA1199, TMEM2L, CCSP1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMEM2L |
| Short name: |
TMEM2L Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TMEM2L (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29213 |
| Gene: |
CEMIP |
More about : CEMIP |
| Long gene name: |
cell migration inducing hyaluronan binding protein |
| Synonyms gene: |
KIAA1199 |
| Synonyms gene name: |
KIAA1199 cell migration inducing protein, hyaluronan binding |
| Synonyms: |
IR2155535 TMEM2L HYBID |
| Synonyms name: |
hyaluronan-binding protein involved in hyaluronan depolymerization |
| Locus: |
15q25, 1 |
| Discovery year: |
2004-06-29 |
| GenBank acession: |
BC020256 |
| Entrez gene record: |
57214 |
| Pubmed identfication: |
14577002 16157444 24573670 |
| RefSeq identity: |
NM_018689 |
| Havana BLAST/BLAT: |
OTTHUMG00000144184 |