| Long name: |
Biotin Conjugated, TMEM2L Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMEM2L |
| Specificity: |
This is a highly specific antibody against TMEM2L |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
140-177/1361 |
| Source: |
KLH conjugated synthetic peptide derived from human TMEM2L |
| Gene ID number: |
57214 |
| Swiss Prot: |
Q8WUJ3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to hyaluronic acid, Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, In collaboration with HSPA5/BIP, Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium, May be involved in hearing, Positively regulates epithelial-mesenchymal transition (EMT), a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes, and hence tumor cell growth, invasion and cancer dissemination, promotes cancer cell migration in a calcium and PKC-dependent manner, Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
IR2155535 TMEM2L HYBID |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMEM2L Conjugated |
| Short name: |
Conjugated, TMEM2L Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TMEM2L (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29213 |
| Gene: |
CEMIP |
More about : CEMIP |
| Long gene name: |
cell migration inducing hyaluronan binding protein |
| Synonyms gene: |
KIAA1199 |
| Synonyms gene name: |
KIAA1199 cell migration inducing protein, hyaluronan binding |
| Synonyms name: |
hyaluronan-binding protein involved in hyaluronan depolymerization |
| Locus: |
15q25, 1 |
| Discovery year: |
2004-06-29 |
| GenBank acession: |
BC020256 |
| Entrez gene record: |
57214 |
| Pubmed identfication: |
14577002 16157444 24573670 |
| RefSeq identity: |
NM_018689 |
| Havana BLAST/BLAT: |
OTTHUMG00000144184 |