| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MHC class I |
| Specificity: |
This antibody reacts specifically with MHC class I |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HLA-A |
| Gene ID: |
93649 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Fibroblasts or neurons however only show a low level of antigen, MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11, The antigen is expressed by all somatic cells at varying levels, which are usually cytotoxic T cells, 5 kDa), MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PERB11, 3 |
| Also known as: |
MHC class I Polyclonal Antibody |
| Other name: |
Anti-MHC class I Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MHC class I |
| Short name: |
Anti-MHC class I (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Major histocompabitility complex class I (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7092 |
| Gene: |
MICC |
More about : MICC |
| Long gene name: |
MHC class I polypeptide-related sequence C (pseudogene) |
| Synonyms gene name: |
MHC class I polypeptide-related sequence C |
| Locus: |
6p22, 1 |
| Discovery year: |
1994-09-07 |
| Entrez gene record: |
100129192 |
| Pubmed identfication: |
8022771 |
| RefSeq identity: |
NG_027534 |
| Havana BLAST/BLAT: |
OTTHUMG00000031078 |