| known also as: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA), Anti-CIITA |
| known also as: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA), CIITA |
| known also as: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA), CIITA |
| known also as: |
CIITA |
| known also as: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA), Anti -CIITA |
| Other names: |
MHC class II transactivator, MHC class II transactivator, MHC class II transactivator type III, N/A, NLR family, acid domain containing, class II, leucine rich repeat and acid domain containing, major histocompatibility complex, nucleotide-binding oligomerization domain, transactivator, CIITA IV |
| Other gene names: |
C2TA, CIITA, CIITA, CIITAIV, MHC2TA, MHC2TA, NLRA, CIITA |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Recognizes human Class II transactivator (CIITA) |
| Purification method: |
Highly Purified by Ion Exchange chromatography |
| Form/Appearance: |
0, pH 7, 01% sodium azide, 2, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile 40-50% glycerol, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA), CIITA |
| Short name: |
C2TA, CIITA IV, CT (Class II Major Histocompatibility Complex Transactivator, Class II Trans Activator, MHC Class II Transactivator, MHC2TA, NLRA) Antibody, CIITA |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
C2TA, CT (Class II Major Histocompatibility aggregate Transactivator, Class II Trans Activator, MHC2TA, Major histocompabitility complex Class II Transactivator, NLRA) (Antibody to), class II, major histocompatibility complex, major histocompatibility complex, transactivator, transactivator IV, class II |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C2TA and CIITAIV and MHC2TA and NLRA, CIITA and IDBG-14377 and ENSG00000179583 and 4261, CIITA and IDBG-636856 and ENSBTAG00000020649 and, Ciita and IDBG-132343 and ENSMUSG00000022504 and 12265, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007568 and aging and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0016605 and PML body and cellular component this GO :0016746 and transferase activity, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046677 and response to antibiotic and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0071257 and cellular response to electrical stimulus and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process, major histocompatibility complex, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0003713 : transcription coactivator activity, this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0016301 : kinase activity and also this GO :0016746 : transferase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0008022 : protein C-terminus binding, this GO :0016301 : kinase activity, this GO :0016746 : transferase activity, this GO :0032403 : protein complex binding, this GO :0033613 : activating transcription factor binding, this GO :0044212 : transcription regulatory region DNA binding, transactivator, transferase activity, transferring acyl groups, transferring acyl groups and also this GO :0032403 : protein complex binding and also this GO :0033613 : activating transcription factor binding and also this GO :0044212 : transcription regulatory region DNA binding, transferring acyl groups and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032966 and negative regulation of collagen biosynthetic process and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034341 and response to interferon-gamma and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045345 and positive regulation of MHC class I biosynthetic process and biological process this GO :0045348 and positive regulation of MHC class II biosynthetic process and biological process this GO :0045892 and negative regulation of transcription, class II |
| Identity: |
7067 |
| Gene: |
CIITA |
More about : CIITA |
| Long gene name: |
class II major histocompatibility complex transactivator |
| Synonyms gene: |
MHC2TA |
| Synonyms gene name: |
MHC class II transactivator class II, major histocompatibility complex, transactivator |
| Synonyms: |
C2TA NLRA |
| Synonyms name: |
NLR family, acid domain containing nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing |
| Locus: |
16p13, 13 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
U18259 |
| Entrez gene record: |
4261 |
| Pubmed identfication: |
8402893 |
| RefSeq identity: |
NM_000246 |
| Classification: |
NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000129753 |
| Locus Specific Databases: |
CIITAbase: Mutation registry for MHCII transactivating protein deficiency (previously known as MHC2TAbase) LRG_49 |