MHC class I Antibody, ALEXA FLUOR 488

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Catalog number: bs-10251R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: MHC class I Antibody, ALEXA FLUOR 488
Quantity: 100ul
Other quantities: 100ul 332€
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More details :

Long name: ALEXA FLUOR 488 Conjugated, MHC class I Polyclonal Antibody
Also known as: Anti-MHC class I PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: MHC class I
Specificity: This is a highly specific antibody against MHC class I
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 60-105/181
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MHC class I
Swiss Prot: G0ZMJ8
Tested applications: IF(IHC-P), FCM
Recommended dilutions: IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity: Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen, Exon 1 encodes the leader peptide, Hundreds of HLA-A alleles have been described, Jul 2008], Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule, The heavy chain is anchored in the membrane, The heavy chain is approximately 45 kDa and its gene contains 8 exons, They are expressed in nearly all cells, This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin), Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation, [provided by RefSeq, and exons 6 and 7 encode the cytoplasmic tail, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, HLA-A belongs to the HLA class I heavy chain paralogues
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: PERB11, 3
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MHC class I Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: MHC class I
Short name: MHC class I Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, Major histocompabitility complex class I (Antibody to)
Alternative technique: antibodies
Identity: 7092
Gene: MICC | More about : MICC
Long gene name: MHC class I polypeptide-related sequence C (pseudogene)
Synonyms gene name: MHC class I polypeptide-related sequence C
Locus: 6p22, 1
Discovery year: 1994-09-07
Entrez gene record: 100129192
Pubmed identfication: 8022771
RefSeq identity: NG_027534
Havana BLAST/BLAT: OTTHUMG00000031078

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