| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IKB zeta |
| Specificity: |
This antibody reacts specifically with IKB zeta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IKB zeta |
| Gene ID: |
64332 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In vitro, Inhibits DNA-binding of RELA and NFKB1/p50, Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation, Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS, May promote apoptosis, Promotes transcription of LCN2 and DEFB4, Seems also to activate NF-kappa-B-mediated transcription, Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer, is recruited to LCN2 promoters, together with NFKB1/p50 and RELA, upon association with NFKB1/p50 has transcriptional activation activity and, Involved in regulation of NF-kappa-B transcription factor complexes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IKBZ, IKBZ_HUMAN, IKBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, IkB-zeta, Ikappa B zeta, IkappaBzeta, MAIL, MAIL protein, Molecule possessing ankyrin repeats induced by lipopolysaccharide, NF-kappa-B inhibitor zeta, NFKBIZ, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta, I-kappa-B-zeta |
| Also known as: |
IKB zeta Polyclonal Antibody |
| Other name: |
Anti-IKB zeta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IKB zeta |
| Short name: |
Anti-IKB zeta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IKB zeta (polyclonal) |
| Alternative technique: |
polyclonals |