| Long name: |
IKB zeta Primary Polyclonal Antibody |
| Also known as: |
IKB zeta PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IKB zeta |
| Specificity: |
This is a highly specific antibody against IKB zeta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IKB zeta |
| Gene ID number: |
64332 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In vitro, Inhibits DNA-binding of RELA and NFKB1/p50, Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation, Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS, May promote apoptosis, Promotes transcription of LCN2 and DEFB4, Seems also to activate NF-kappa-B-mediated transcription, Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer, is recruited to LCN2 promoters, together with NFKB1/p50 and RELA, upon association with NFKB1/p50 has transcriptional activation activity and, Involved in regulation of NF-kappa-B transcription factor complexes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
IKBZ, IKBZ_HUMAN, IKBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, IkB-zeta, Ikappa B zeta, IkappaBzeta, MAIL, MAIL protein, Molecule possessing ankyrin repeats induced by lipopolysaccharide, NF-kappa-B inhibitor zeta, NFKBIZ, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta, I-kappa-B-zeta |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKB zeta |
| Short name: |
IKB zeta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IKB zeta (Antibody to) |
| Alternative technique: |
antibodies |