| Long name: |
Biotin Conjugated, IKB zeta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IKB zeta |
| Specificity: |
This is a highly specific antibody against IKB zeta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human IKB zeta |
| Gene ID number: |
64332 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In vitro, Inhibits DNA-binding of RELA and NFKB1/p50, Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation, Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS, May promote apoptosis, Promotes transcription of LCN2 and DEFB4, Seems also to activate NF-kappa-B-mediated transcription, Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer, is recruited to LCN2 promoters, together with NFKB1/p50 and RELA, upon association with NFKB1/p50 has transcriptional activation activity and, Involved in regulation of NF-kappa-B transcription factor complexes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
IKBZ, IKBZ_HUMAN, IKBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, IkB-zeta, Ikappa B zeta, IkappaBzeta, MAIL, MAIL protein, Molecule possessing ankyrin repeats induced by lipopolysaccharide, NF-kappa-B inhibitor zeta, NFKBIZ, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta, I-kappa-B-zeta |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKB zeta Conjugated |
| Short name: |
Conjugated, IKB zeta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, IKB zeta (Antibody to) |
| Alternative technique: |
antibodies |