| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CIDEC |
| Specificity: |
there is a chance that this antibody will react with this protein in those two species based on homology, CIDEC, Due to the similarity of this protein with CIDEA in Mouse and Rat |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CIDEC |
| Gene ID: |
63924 |
| Swiss Prot: |
Q96AQ7 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
As mature adipocytes, At focal contact sites between lipid droplets, ID2 and XDH, Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1, May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression, SOCS3, TGFB1, TGFBR1, The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair, When overexpressed in preadipocytes, are quite resistant to apoptotic stimuli, including SOCS1, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets, that express high CIDEC levels, the physiological significance of its role in apoptosis is unclear, thereby restricting lipolysis and favoring storage, Binds to lipid droplets and regulates their enlargement |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CIDE-3 FLJ20871 Fsp27 |
| Also known as: |
CIDEC Polyclonal Antibody |
| Other name: |
Anti-CIDEC Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CIDEC |
| Short name: |
Anti-CIDEC (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
45kDa, ALEXA Fluor 594, alpha polypeptide-like effector c (polyclonal), antibody to-cellular death-inducing Desoxyribonucleic acid fragmentation factor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CIDEC and IDBG-16636 and ENSG00000187288 and 63924, CIDEC and IDBG-644696 and ENSBTAG00000007969 and 534607, Cidec and IDBG-176827 and ENSMUSG00000030278 and 14311, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0034389 and lipid particle organization and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0097194 and execution phase of apoptosis and biological process, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005811 and lipid particle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, cell death-inducing DFFA-like effector c |
| Identity: |
24229 |
| Gene: |
CIDEC |
More about : CIDEC |
| Long gene name: |
cell death inducing DFFA like effector c |
| Synonyms gene name: |
cell death-inducing DFFA-like effector c |
| Locus: |
3p25, 3 |
| Discovery year: |
2004-07-26 |
| Entrez gene record: |
63924 |
| Pubmed identfication: |
12429024 |
| RefSeq identity: |
NM_022094 |
| Havana BLAST/BLAT: |
OTTHUMG00000128522 |