| Long name: |
Cy7 Conjugated, CIDEC Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CIDEC |
| Specificity: |
Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology, This is a highly specific antibody against CIDEC |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
110-160/238 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human CIDEC |
| Gene ID number: |
63924 |
| Swiss Prot: |
Q96AQ7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As mature adipocytes, At focal contact sites between lipid droplets, ID2 and XDH, Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1, May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression, SOCS3, TGFB1, TGFBR1, The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair, When overexpressed in preadipocytes, are quite resistant to apoptotic stimuli, including SOCS1, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets, that express high CIDEC levels, the physiological significance of its role in apoptosis is unclear, thereby restricting lipolysis and favoring storage, Binds to lipid droplets and regulates their enlargement |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
CIDE-3 FLJ20871 Fsp27 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
CIDEC Conjugated |
| Short name: |
Conjugated, CIDEC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
45kDa, alpha polypeptide-like effector c (Antibody to), cyanine 7 coupled, cellular death-inducing Desoxyribonucleic acid fragmentation factor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CIDEC and IDBG-16636 and ENSG00000187288 and 63924, CIDEC and IDBG-644696 and ENSBTAG00000007969 and 534607, Cidec and IDBG-176827 and ENSMUSG00000030278 and 14311, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0034389 and lipid particle organization and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0097194 and execution phase of apoptosis and biological process, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005811 and lipid particle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, cell death-inducing DFFA-like effector c |
| Identity: |
24229 |
| Gene: |
CIDEC |
More about : CIDEC |
| Long gene name: |
cell death inducing DFFA like effector c |
| Synonyms gene name: |
cell death-inducing DFFA-like effector c |
| Locus: |
3p25, 3 |
| Discovery year: |
2004-07-26 |
| Entrez gene record: |
63924 |
| Pubmed identfication: |
12429024 |
| RefSeq identity: |
NM_022094 |
| Havana BLAST/BLAT: |
OTTHUMG00000128522 |