| Long name: |
ALEXA FLUOR 647 Conjugated, CIDEC Polyclonal Antibody |
| Also known as: |
Anti-CIDEC PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CIDEC |
| Specificity: |
This is a highly specific antibody against CIDEC |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
110-160/238 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CIDEC |
| Gene ID Number: |
63924 |
| Swiss Prot: |
Q96AQ7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As mature adipocytes, At focal contact sites between lipid droplets, ID2 and XDH, Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1, May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression, SOCS3, TGFB1, TGFBR1, The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair, When overexpressed in preadipocytes, are quite resistant to apoptotic stimuli, including SOCS1, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets, that express high CIDEC levels, the physiological significance of its role in apoptosis is unclear, thereby restricting lipolysis and favoring storage, Binds to lipid droplets and regulates their enlargement |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CIDE-3 FLJ20871 Fsp27 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CIDEC Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CIDEC |
| Short name: |
CIDEC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
45kDa, ALEXA FLUOR 647, alpha polypeptide-like effector c (Antibody to), cellular death-inducing Desoxyribonucleic acid fragmentation factor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CIDEC and IDBG-16636 and ENSG00000187288 and 63924, CIDEC and IDBG-644696 and ENSBTAG00000007969 and 534607, Cidec and IDBG-176827 and ENSMUSG00000030278 and 14311, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0034389 and lipid particle organization and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0097194 and execution phase of apoptosis and biological process, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005811 and lipid particle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, cell death-inducing DFFA-like effector c |
| Identity: |
24229 |
| Gene: |
CIDEC |
More about : CIDEC |
| Long gene name: |
cell death inducing DFFA like effector c |
| Synonyms gene name: |
cell death-inducing DFFA-like effector c |
| Locus: |
3p25, 3 |
| Discovery year: |
2004-07-26 |
| Entrez gene record: |
63924 |
| Pubmed identfication: |
12429024 |
| RefSeq identity: |
NM_022094 |
| Havana BLAST/BLAT: |
OTTHUMG00000128522 |