| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TSLC1 |
| Specificity: |
This antibody reacts specifically with TSLC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CADM1/TSLC1 |
| Gene ID: |
23705 |
| Swiss Prot: |
Q9BY67 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity), Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells, Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner, CADM1, In mast cells, Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo, May be involved in neuronal migration, May contribute to the less invasive phenotypes of lepidic growth tumor cells, May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa, and fasciculation on the axons of differentiating neurons, axon growth, is essential for development and survival of mast cells in vivo, may mediate attachment to and promote communication with nerves, pathfinding, together with MITF, Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NECL2 ST17 BL2 SYNCAM IGSF4A Necl-2 SYNCAM1 RA175 |
| Also known as: |
TSLC1 Polyclonal Antibody |
| Other name: |
Anti-TSLC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TSLC1 |
| Short name: |
Anti-TSLC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TSLC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5951 |
| Gene: |
CADM1 |
More about : CADM1 |
| Long gene name: |
cell adhesion molecule 1 |
| Synonyms gene: |
TSLC1 IGSF4 |
| Synonyms gene name: |
member 4 , tumor suppressor in lung cancer 1 immunoglobulin superfamily |
| Synonyms name: |
nectin-like 2 |
| Locus: |
11q23, 3 |
| Discovery year: |
1998-11-02 |
| GenBank acession: |
AB017563 |
| Entrez gene record: |
23705 |
| Pubmed identfication: |
10610705 |
| RefSeq identity: |
NM_014333 |
| Classification: |
C2-set domain containing Immunoglobulin like domain containing V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168202 |