| Long name: |
FITC Conjugated, TSLC1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TSLC1 |
| Specificity: |
This is a highly specific antibody against TSLC1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
70-120/442 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CADM1/TSLC1 |
| Gene ID number: |
23705 |
| Swiss Prot: |
Q9BY67 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity), Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells, Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner, CADM1, In mast cells, Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo, May be involved in neuronal migration, May contribute to the less invasive phenotypes of lepidic growth tumor cells, May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa, and fasciculation on the axons of differentiating neurons, axon growth, is essential for development and survival of mast cells in vivo, may mediate attachment to and promote communication with nerves, pathfinding, together with MITF, Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
NECL2 ST17 BL2 SYNCAM IGSF4A Necl-2 SYNCAM1 RA175 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TSLC1 Conjugated |
| Short name: |
FITC Conjugated, TSLC1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TSLC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5951 |
| Gene: |
CADM1 |
More about : CADM1 |
| Long gene name: |
cell adhesion molecule 1 |
| Synonyms gene: |
TSLC1 IGSF4 |
| Synonyms gene name: |
member 4 , tumor suppressor in lung cancer 1 immunoglobulin superfamily |
| Synonyms name: |
nectin-like 2 |
| Locus: |
11q23, 3 |
| Discovery year: |
1998-11-02 |
| GenBank acession: |
AB017563 |
| Entrez gene record: |
23705 |
| Pubmed identfication: |
10610705 |
| RefSeq identity: |
NM_014333 |
| Classification: |
C2-set domain containing Immunoglobulin like domain containing V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168202 |