Anti-MEK5(Ser311+Thr315) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be637b8612b Buy Now
Price:	489 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	Anti-MEK5(Ser311+Thr315) (Polyclonal), ALEXA Fluor 594
Quantity:	100 microliters
Related search:	kinase polyclonal antibody protein serthr species nbsp activated

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	MEK5 Ser311+Thr315
Specificity:	This antibody reacts specifically with MEK5(Ser311+Thr315)
Modification:	Phosphorylation
Modification site:	Ser311+Thr315
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser311+Thr315
Gene ID:	5607
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	(MAP kinase kinase family), It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, It is not phosphorylated by RAFA, MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle, RAFB or RAFC and it may interact with GTPases such as CDC42, The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation, This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, This kinase specifically interacts with and activates MAPK7/ERK5, and not with another MAP kinase like P38, as well as by atypical protein kinase C isoforms (aPKCs), MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	MEK5 MAPKK5 HsT17454
Also known as:	MEK5(Ser311+Thr315) Polyclonal Antibody
Other name:	Anti-MEK5(Ser311+Thr315) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	MEK5(Ser311+Thr315)
Short name:	Anti-MEK5(Ser311+Thr315) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-MEK5(Ser311+Thr315) (polyclonal)
Alternative technique:	polyclonals
Identity:	6845
Gene:	MAP2K5 | More about : MAP2K5
Long gene name:	mitogen-activated protein kinase kinase 5
Synonyms gene:	PRKMK5
Locus:	15q23
Discovery year:	1997-11-11
GenBank acession:	U25265
Entrez gene record:	5607
Pubmed identfication:	7759517
RefSeq identity:	NM_145162
Classification:	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000133264

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