| Long name: |
MEK5(Ser311+Thr315) Primary Polyclonal Antibody |
| Also known as: |
MEK5(Ser311+Thr315) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MEK5 Ser311+Thr315 |
| Specificity: |
This is a highly specific antibody against MEK5 Ser311+Thr315 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser311+Thr315 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser311+Thr315 |
| Gene ID number: |
5607 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
(MAP kinase kinase family), It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, It is not phosphorylated by RAFA, MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle, RAFB or RAFC and it may interact with GTPases such as CDC42, The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation, This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, This kinase specifically interacts with and activates MAPK7/ERK5, and not with another MAP kinase like P38, as well as by atypical protein kinase C isoforms (aPKCs), MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Dual specicity mitogen activated protein kinase kinase 5, EC 2, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAP2K5, MAPK/ERK kinase 5, MAPKK5, PRKMK5, 2, 7, 12, MAP2K5 phospho S311/T315 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MEK5(Ser311+Thr315) |
| Short name: |
MEK5(Ser311+Thr315) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MEK5(Ser311+Thr315) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6845 |
| Gene: |
MAP2K5 |
More about : MAP2K5 |
| Long gene name: |
mitogen-activated protein kinase kinase 5 |
| Synonyms gene: |
PRKMK5 |
| Synonyms: |
MEK5 MAPKK5 HsT17454 |
| Locus: |
15q23 |
| Discovery year: |
1997-11-11 |
| GenBank acession: |
U25265 |
| Entrez gene record: |
5607 |
| Pubmed identfication: |
7759517 |
| RefSeq identity: |
NM_145162 |
| Classification: |
Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000133264 |