Anti-CREB-1(Ser142) (Polyclonal), ALEXA Fluor 594

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Catalog number: GENTAUR-58be634748405
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: Anti-CREB-1(Ser142) (Polyclonal), ALEXA Fluor 594
Quantity: 100ul
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More details :

Type: Conjugated Primary Antibody
Conjugated with: 594, ALEXA FLUOR®
Host organism: Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide: CREB-1Ser142
Specificity: This antibody reacts specifically with CREB-1(Ser142)
Modification: Phosphorylation
Modification site: Ser142
Clonality: Polyclonal Antibody
Clone: Polyclonal Antibodies
Concentration: 1ug per 1ul
Antigen Source: KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser142 [DL(p-S)SD]
Gene ID: 1385
Applications: IF(IHC-P)
Applications with corresponding dilutions: IF(IHC-P)(1:50-200)
Cross reactive species: Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details: However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information: ATF-1, Although each of the ATF/CREB proteins bind CREs in their homodimeric form, CREB-2, It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), TGACCTCA, The best characterized members of this gene family include CREB-1, both within the ATF/CREB family and with members of the AP-1 transcription factor family, in cerain instances they also bind as heterodimers, these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains, which may reprecent a CREB co-activator, ATF-2, ATF-3and ATF-4, The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide
Purification method: Purified by Protein A
Storage: 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission: 590nm/617nm
Synonyms: CREB, CREB 1, CREB1, CREB1, MGC9284, Transactivator protein, cAMP response element binding protein, cAMP responsive element binding protein 1, Active transcription factor CREB
Also known as: CREB-1(Ser142) Polyclonal Antibody
Other name: Anti-CREB-1(Ser142) Polyclonal
Advisory: For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties: For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Group: Polyclonals and antibodies
About: The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target: CREB-1(Ser142)
Short name: Anti-CREB-1(Ser142) (Polyclonal) Fluor 594
Technique: Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
Label: ALEXA
Alternative name: ALEXA Fluor 594, antibody to-CREB-1(Ser142) (polyclonal)
Alternative technique: polyclonals

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