| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CREB-H/CREB3L3 |
| Specificity: |
This antibody reacts specifically with CREB-H/CREB3L3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CREB-H |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, CREB3L3 functions as a dimer and contains one leucine zipper domain, CREB3L3 functions as a transcription factor that, CREB3L3 is underexpressed in hepatocellular carcinoma, Expressed exclusively in liver, Three isoforms of CREB3L3 exist due to alternative splicing events, a KDEL-like sequence and a bZIP domain, during ER stress, in response to ER stress, is cleaved and translocated to the nucleus, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR), suggesting a possible role as a tumor suppressor, through which it conveys its DNA binding ability, CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CREB-H |
| Also known as: |
CREB-H/CREB3L3 Polyclonal Antibody |
| Other name: |
Anti-CREB-H/CREB3L3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CREB-H/CREB3L3 |
| Short name: |
Anti-CREB-H/CREB3L3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CREB-H/CREB3L3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18855 |
| Gene: |
CREB3L3 |
More about : CREB3L3 |
| Long gene name: |
cAMP responsive element binding protein 3 like 3 |
| Locus: |
19p13, 3 |
| Discovery year: |
2003-12-09 |
| Entrez gene record: |
84699 |
| Pubmed identfication: |
11353085 |
| RefSeq identity: |
NM_032607 |
| Classification: |
Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000181846 |