| Long name: |
Cy7 Conjugated, CREB-1(Ser142) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CREB-1Ser142 |
| Specificity: |
This is a highly specific antibody against CREB-1Ser142 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser142 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser142 [DL(p-S)SD] |
| Gene ID number: |
1385 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ATF-1, Although each of the ATF/CREB proteins bind CREs in their homodimeric form, CREB-2, It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), TGACCTCA, The best characterized members of this gene family include CREB-1, both within the ATF/CREB family and with members of the AP-1 transcription factor family, in cerain instances they also bind as heterodimers, these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains, which may reprecent a CREB co-activator, ATF-2, ATF-3and ATF-4, The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
CREB, CREB 1, CREB1, CREB1, MGC9284, Transactivator protein, cAMP response element binding protein, cAMP responsive element binding protein 1, Active transcription factor CREB |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
CREB-1(Ser142) Conjugated |
| Short name: |
Conjugated, CREB-1(Ser142) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, CREB-1(Ser142) (Antibody to) |
| Alternative technique: |
antibodies |