Anti-SHC (Tyr317) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be61a067c68 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Anti-SHC (Tyr317) (Polyclonal), ALEXA Fluor 594
Quantity:	100ul
Related search:	shc gene polyclonal antibody protein the nbsp act

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	SHC Tyr317
Specificity:	This antibody reacts specifically with SHC (Tyr317)
Modification:	Phosphorylation
Modification site:	Tyr317
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human SHC around the phosphorylation site of Tyr317
Gene ID:	6464
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	Adjacent to the SH2 region is a glycine and proline rich region, SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway, The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways, These 2 proteins differ in their N terminals, both containing a C-terminal SH2 domain, The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	p66 ShcA
Also known as:	SHC (Tyr317) Polyclonal Antibody
Other name:	Anti-SHC (Tyr317) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	SHC (Tyr317)
Short name:	Anti-SHC (Tyr317) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-SHC (Tyr317) (polyclonal)
Alternative technique:	polyclonals
Identity:	10840
Gene:	SHC1 | More about : SHC1
Long gene name:	SHC adaptor protein 1
Synonyms gene:	SHC
Synonyms gene name:	SHC (Src homology 2 domain-containing) transforming protein 1
Locus:	1q21, 3
Discovery year:	1993-02-17
GenBank acession:	U73377
Entrez gene record:	6464
Pubmed identfication:	1623525
RefSeq identity:	NM_183001
Classification:	SH2 domain containing
Havana BLAST/BLAT:	OTTHUMG00000037295

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