| Long name: |
Cy5, 5 Conjugated, SHC (Tyr317) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHC Tyr317 |
| Specificity: |
This is a highly specific antibody against SHC Tyr317 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr317 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SHC around the phosphorylation site of Tyr317 |
| Gene ID number: |
6464 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Adjacent to the SH2 region is a glycine and proline rich region, SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway, The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways, These 2 proteins differ in their N terminals, both containing a C-terminal SH2 domain, The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
p66 ShcA |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
SHC (Tyr317) Conjugated |
| Short name: |
Conjugated, SHC (Tyr317) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, SHC (Tyr317) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10840 |
| Gene: |
SHC1 |
More about : SHC1 |
| Long gene name: |
SHC adaptor protein 1 |
| Synonyms gene: |
SHC |
| Synonyms gene name: |
SHC (Src homology 2 domain-containing) transforming protein 1 |
| Locus: |
1q21, 3 |
| Discovery year: |
1993-02-17 |
| GenBank acession: |
U73377 |
| Entrez gene record: |
6464 |
| Pubmed identfication: |
1623525 |
| RefSeq identity: |
NM_183001 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037295 |