Anti-PFK2 (Ser467) (Polyclonal), ALEXA Fluor 594

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Catalog number: GENTAUR-58be61876e10b
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: Anti-PFK2 (Ser467) (Polyclonal), ALEXA Fluor 594
Quantity: 0.1ml
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More details :

Type: Conjugated Primary Antibody
Conjugated with: 594, ALEXA FLUOR®
Host organism: Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide: PFK2 Ser467
Specificity: PFK2 (Ser467), This phosphorylated site is homologous to that of Ser467 in Mouse and Ser496 in Rat
Modification: Phosphorylation
Modification site: Ser467
Clonality: Polyclonal Antibody
Clone: Polyclonal Antibodies
Concentration: 1ug per 1ul
Subcellular locations: Nucleus
Antigen Source: KLH conjugated synthetic phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467
Gene ID: 5209
Swiss Prot: Q16875
Applications: IF(IHC-P)
Applications with corresponding dilutions: IF(IHC-P)(1:50-200)
Cross reactive species: Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details: However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information: Fructose-2, Glycolytic flux is key to tumour growth, Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth, which catalyses a key step in the glycoytic pathway, 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2, 6-bisphosphate, 6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1)
Purification method: Purified by Protein A
Storage: 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission: 590nm/617nm
Synonyms: 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6PF-2-K/Fru-2, IPFK2, PFK/FBPase 3, PFKFB3, Renal carcinoma antigen NY-REN-56, iPFK-2, 6-P2ase 3, 6-P2ase brain/placenta-type isozyme, 6-bisphosphatase 3, PFK2
Also known as: PFK2 (Ser467) Polyclonal Antibody
Other name: Anti-PFK2 (Ser467) Polyclonal
Advisory: For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties: For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Group: Polyclonals and antibodies
About: The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target: PFK2 (Ser467)
Short name: Anti-PFK2 (Ser467) (Polyclonal) Fluor 594
Technique: Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
Label: ALEXA
Alternative name: ALEXA Fluor 594, antibody to-PFK2 (Ser467) (polyclonal)
Alternative technique: polyclonals

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