| Long name: |
ALEXA FLUOR 488 Conjugated, PFK2 (Ser467) Polyclonal Antibody |
| Also known as: |
Anti-PFK2 Ser467 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PFK2 Ser467 |
| Specificity: |
This is a highly specific antibody against PFK2 Ser467 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser467 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
458-520/520 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467 |
| Gene ID Number: |
5209 |
| Swiss Prot: |
Q16875 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Fructose-2, Glycolytic flux is key to tumour growth, Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth, which catalyses a key step in the glycoytic pathway, 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2, 6-bisphosphate, 6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6PF-2-K/Fru-2, IPFK2, PFK/FBPase 3, PFKFB3, Renal carcinoma antigen NY-REN-56, iPFK-2, 6-P2ase 3, 6-P2ase brain/placenta-type isozyme, 6-bisphosphatase 3, PFK2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PFK2 (Ser467) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PFK2 (Ser467) |
| Short name: |
PFK2 (Ser467) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PFK2 (Ser467) (Antibody to) |
| Alternative technique: |
antibodies |