| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DEP1/PTPRJ |
| Specificity: |
This antibody reacts specifically with DEP1/PTPRJ |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PTPRJ |
| Gene ID: |
5795 |
| Swiss Prot: |
Q12913 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
EGFR, Enhances the barrier function of epithelial junctions during reassembly, FLT3, Involved in vascular development, KDR, LYN, MAPK1, MAPK3, MET, Negative regulator of EGFR signaling pathway, Negative regulator of PDGF-stimulated cell migration, Negative regulator of cell proliferation, Negatively regulates T-cell receptor (TCR) signaling, OCLN, PDGFRB, PIK3R1 and PIK3R2, Plays a role in cell adhesion, Positive regulator of endothelial cell survival, Positive regulator of platelet activation and thrombosis, Positively affects cell-matrix adhesion, RET (variant MEN2A), Regulator of macrophage adhesion and spreading, SRC, TJP1, Upon T-cell TCR activation, as well as of VEGF-induced SRC and AKT activation, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling, it is up-regulated and excluded from the immunological synapses, migration, proliferation and differentiation, through EGFR dephosphorylation, through KDR dephosphorylation, through dephosphorylation of PDGFR, while upon T-cell-antigen presenting cells (APC) disengagement, Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DEP1 HPTPeta CD148 |
| Also known as: |
DEP1/PTPRJ Polyclonal Antibody |
| Other name: |
Anti-DEP1/PTPRJ Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DEP1/PTPRJ |
| Short name: |
Anti-DEP1/PTPRJ (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DEP1/PTPRJ (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9673 |
| Gene: |
PTPRJ |
More about : PTPRJ |
| Long gene name: |
protein tyrosine phosphatase, receptor type J |
| Locus: |
11p11, 2 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
U10886 |
| Entrez gene record: |
5795 |
| Pubmed identfication: |
7937872 7994032 |
| Classification: |
Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000166573 |