| Long name: |
DEP1/PTPRJ Primary Polyclonal Antibody |
| Also known as: |
DEP1/PTPRJ PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DEP1/PTPRJ |
| Specificity: |
This is a highly specific antibody against DEP1/PTPRJ |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
850-890/1337 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PTPRJ |
| Gene ID number: |
5795 |
| Swiss Prot: |
Q12913 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
EGFR, Enhances the barrier function of epithelial junctions during reassembly, FLT3, Involved in vascular development, KDR, LYN, MAPK1, MAPK3, MET, Negative regulator of EGFR signaling pathway, Negative regulator of PDGF-stimulated cell migration, Negative regulator of cell proliferation, Negatively regulates T-cell receptor (TCR) signaling, OCLN, PDGFRB, PIK3R1 and PIK3R2, Plays a role in cell adhesion, Positive regulator of endothelial cell survival, Positive regulator of platelet activation and thrombosis, Positively affects cell-matrix adhesion, RET (variant MEN2A), Regulator of macrophage adhesion and spreading, SRC, TJP1, Upon T-cell TCR activation, as well as of VEGF-induced SRC and AKT activation, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling, it is up-regulated and excluded from the immunological synapses, migration, proliferation and differentiation, through EGFR dephosphorylation, through KDR dephosphorylation, through dephosphorylation of PDGFR, while upon T-cell-antigen presenting cells (APC) disengagement, Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD148, DEP-1, Density-enhanced phosphatase 1, HPTP eta, HPTPeta, PTPRJ, Protein-tyrosine phosphatase eta, Protein-tyrosine phosphatase receptor type J, R-PTP-ETA, R-PTP-J, Receptor-type tyrosine-protein phosphatase eta, SCC1, DEP1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DEP1/PTPRJ |
| Short name: |
DEP1/PTPRJ Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DEP1/PTPRJ (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9673 |
| Gene: |
PTPRJ |
More about : PTPRJ |
| Long gene name: |
protein tyrosine phosphatase, receptor type J |
| Synonyms: |
DEP1 HPTPeta CD148 |
| Locus: |
11p11, 2 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
U10886 |
| Entrez gene record: |
5795 |
| Pubmed identfication: |
7937872 7994032 |
| Classification: |
Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000166573 |