| Long name: |
FITC Conjugated, DEP1/PTPRJ Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DEP1/PTPRJ |
| Specificity: |
This is a highly specific antibody against DEP1/PTPRJ |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
850-890/1337 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PTPRJ |
| Gene ID number: |
5795 |
| Swiss Prot: |
Q12913 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
EGFR, Enhances the barrier function of epithelial junctions during reassembly, FLT3, Involved in vascular development, KDR, LYN, MAPK1, MAPK3, MET, Negative regulator of EGFR signaling pathway, Negative regulator of PDGF-stimulated cell migration, Negative regulator of cell proliferation, Negatively regulates T-cell receptor (TCR) signaling, OCLN, PDGFRB, PIK3R1 and PIK3R2, Plays a role in cell adhesion, Positive regulator of endothelial cell survival, Positive regulator of platelet activation and thrombosis, Positively affects cell-matrix adhesion, RET (variant MEN2A), Regulator of macrophage adhesion and spreading, SRC, TJP1, Upon T-cell TCR activation, as well as of VEGF-induced SRC and AKT activation, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling, it is up-regulated and excluded from the immunological synapses, migration, proliferation and differentiation, through EGFR dephosphorylation, through KDR dephosphorylation, through dephosphorylation of PDGFR, while upon T-cell-antigen presenting cells (APC) disengagement, Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DEP1 HPTPeta CD148 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DEP1/PTPRJ Conjugated |
| Short name: |
FITC Conjugated, DEP1/PTPRJ Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DEP1/PTPRJ (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9673 |
| Gene: |
PTPRJ |
More about : PTPRJ |
| Long gene name: |
protein tyrosine phosphatase, receptor type J |
| Locus: |
11p11, 2 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
U10886 |
| Entrez gene record: |
5795 |
| Pubmed identfication: |
7937872 7994032 |
| Classification: |
Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000166573 |