| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SLAMF7/CD319/CS1 |
| Specificity: |
This antibody reacts specifically with SLAMF7/CD319/CS1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLAMF7 |
| Swiss Prot: |
Q9NQ25 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
B-, Expression was detected in NK cells, Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway, Isoform 3 does not mediate any activation, It may play a role in lymphocyte adhesion, NK-cell line but not in promyelocytic, SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro), SLAMF7 is expressed in spleen, The isoform 3 is expressed at much lower level than isoform 1, There are three named isoforms, activated B-cells, appendix, bone marrow, lung and trachea, lymph node, or T-cell lines, peripheral blood leukocytes, small intestine, stomach, SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CRACC 19A CS1 CD319 |
| Also known as: |
SLAMF7/CD319/CS1 Polyclonal Antibody |
| Other name: |
Anti-SLAMF7/CD319/CS1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SLAMF7/CD319/CS1 |
| Short name: |
Anti-SLAMF7/CD319/CS1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SLAM family member 7/CD319/CS1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, SLAMF7 and IDBG-104088 and ENSG00000026751 and 57823, SLAMF7 and IDBG-630522 and ENSBTAG00000001197 and 790164, Slamf7 and IDBG-204760 and ENSMUSG00000038179 and 75345, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030101 and natural killer cell activation and biological process this GO :0032814 and regulation of natural killer cell activation and biological process this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0045087 and innate immune response and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, SLAM family member 7 |
| Identity: |
21394 |
| Gene: |
SLAMF7 |
More about : SLAMF7 |
| Long gene name: |
SLAM family member 7 |
| Locus: |
1q23, 3 |
| Discovery year: |
2003-10-29 |
| GenBank acession: |
AB027233 |
| Entrez gene record: |
57823 |
| Pubmed identfication: |
11802771 11220635 |
| RefSeq identity: |
NM_021181 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024008 |