| Long name: |
FITC Conjugated, SLAMF7/CD319/CS1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLAMF7/CD319/CS1 |
| Specificity: |
This is a highly specific antibody against SLAMF7/CD319/CS1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
80-125/335 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human SLAMF7 |
| Swiss Prot: |
Q9NQ25 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
B-, Expression was detected in NK cells, Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway, Isoform 3 does not mediate any activation, It may play a role in lymphocyte adhesion, NK-cell line but not in promyelocytic, SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro), SLAMF7 is expressed in spleen, The isoform 3 is expressed at much lower level than isoform 1, There are three named isoforms, activated B-cells, appendix, bone marrow, lung and trachea, lymph node, or T-cell lines, peripheral blood leukocytes, small intestine, stomach, SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CRACC 19A CS1 CD319 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLAMF7/CD319/CS1 Conjugated |
| Short name: |
FITC Conjugated, SLAMF7/CD319/CS1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SLAM family member 7/CD319/CS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, SLAMF7 and IDBG-104088 and ENSG00000026751 and 57823, SLAMF7 and IDBG-630522 and ENSBTAG00000001197 and 790164, Slamf7 and IDBG-204760 and ENSMUSG00000038179 and 75345, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030101 and natural killer cell activation and biological process this GO :0032814 and regulation of natural killer cell activation and biological process this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0045087 and innate immune response and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, SLAM family member 7 |
| Identity: |
21394 |
| Gene: |
SLAMF7 |
More about : SLAMF7 |
| Long gene name: |
SLAM family member 7 |
| Locus: |
1q23, 3 |
| Discovery year: |
2003-10-29 |
| GenBank acession: |
AB027233 |
| Entrez gene record: |
57823 |
| Pubmed identfication: |
11802771 11220635 |
| RefSeq identity: |
NM_021181 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024008 |