| Long name: |
SLAMF7/CD319/CS1 Primary Polyclonal Antibody |
| Also known as: |
SLAMF7/CD319/CS1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SLAMF7/CD319/CS1 |
| Specificity: |
This is a highly specific antibody against SLAMF7/CD319/CS1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
80-125/335 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLAMF7 |
| Swiss Prot: |
Q9NQ25 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
B-, Expression was detected in NK cells, Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway, Isoform 3 does not mediate any activation, It may play a role in lymphocyte adhesion, NK-cell line but not in promyelocytic, SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro), SLAMF7 is expressed in spleen, The isoform 3 is expressed at much lower level than isoform 1, There are three named isoforms, activated B-cells, appendix, bone marrow, lung and trachea, lymph node, or T-cell lines, peripheral blood leukocytes, small intestine, stomach, SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
19A24 protein, CD 319, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CD319, CD319 antigen, CRACC, CS1, Membrane protein FOAP 12, Novel LY9 lymphocyte antigen 9 like protein, Novel Ly9, Protein 19A, SLAM family member 7, SLAMF 7, 19A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLAMF7/CD319/CS1 |
| Short name: |
SLAMF7/CD319/CS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLAM family member 7/CD319/CS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, SLAMF7 and IDBG-104088 and ENSG00000026751 and 57823, SLAMF7 and IDBG-630522 and ENSBTAG00000001197 and 790164, Slamf7 and IDBG-204760 and ENSMUSG00000038179 and 75345, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030101 and natural killer cell activation and biological process this GO :0032814 and regulation of natural killer cell activation and biological process this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0045087 and innate immune response and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, SLAM family member 7 |
| Identity: |
21394 |
| Gene: |
SLAMF7 |
More about : SLAMF7 |
| Long gene name: |
SLAM family member 7 |
| Synonyms: |
CRACC 19A CS1 CD319 |
| Locus: |
1q23, 3 |
| Discovery year: |
2003-10-29 |
| GenBank acession: |
AB027233 |
| Entrez gene record: |
57823 |
| Pubmed identfication: |
11802771 11220635 |
| RefSeq identity: |
NM_021181 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024008 |