| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FAIM3 |
| Specificity: |
This antibody reacts specifically with FAIM3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Secreted, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FAIM3 |
| Gene ID: |
9214 |
| Swiss Prot: |
O60667 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation, Protects cells from FAS-, Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL, rather than blocking apoptotic signals downstream, May play a role in the immune system processes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TOSO |
| Also known as: |
FAIM3 Polyclonal Antibody |
| Other name: |
Anti-FAIM3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FAIM3 |
| Short name: |
Anti-FAIM3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 6) apoptotic inhibitory molecule 3 (polyclonal), antibody to-Fas (TNF receptor superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, FAIM3 and IDBG-106292 and ENSG00000162894 and 9214, FAIM3 and IDBG-629197 and ENSBTAG00000019796 and 511564, FCMR and TOSO, Faim3 and IDBG-190537 and ENSMUSG00000042474 and 69169, this GO :0002376 and immune system process and biological process this GO :0005576 and extracellular region and cellular component this GO :0006968 and cellular defense response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, Fas apoptotic inhibitory molecule 3 |
| Identity: |
14315 |
| Gene: |
FCMR |
More about : FCMR |
| Long gene name: |
Fc fragment of IgM receptor |
| Synonyms gene: |
FAIM3 |
| Synonyms gene name: |
Fas apoptotic inhibitory molecule 3 |
| Locus: |
1q32, 1 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF057557 |
| Entrez gene record: |
9214 |
| Pubmed identfication: |
9586636 1563211 25888699 |
| RefSeq identity: |
NM_005449 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036457 |