| Long name: |
FAIM3 Primary Polyclonal Antibody |
| Also known as: |
FAIM3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FAIM3 |
| Specificity: |
This is a highly specific antibody against FAIM3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
80-130/390 |
| Subcellular location: |
Cell membrane, Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FAIM3 |
| Gene ID number: |
9214 |
| Swiss Prot: |
O60667 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation, Protects cells from FAS-, Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL, rather than blocking apoptotic signals downstream, May play a role in the immune system processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FAIM3, Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso, TOSO |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAIM3 |
| Short name: |
FAIM3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6) apoptotic inhibitory molecule 3 (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, FAIM3 and IDBG-106292 and ENSG00000162894 and 9214, FAIM3 and IDBG-629197 and ENSBTAG00000019796 and 511564, FCMR and TOSO, Faim3 and IDBG-190537 and ENSMUSG00000042474 and 69169, this GO :0002376 and immune system process and biological process this GO :0005576 and extracellular region and cellular component this GO :0006968 and cellular defense response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, Fas apoptotic inhibitory molecule 3 |
| Identity: |
14315 |
| Gene: |
FCMR |
More about : FCMR |
| Long gene name: |
Fc fragment of IgM receptor |
| Synonyms gene: |
FAIM3 |
| Synonyms gene name: |
Fas apoptotic inhibitory molecule 3 |
| Synonyms: |
TOSO |
| Locus: |
1q32, 1 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF057557 |
| Entrez gene record: |
9214 |
| Pubmed identfication: |
9586636 1563211 25888699 |
| RefSeq identity: |
NM_005449 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036457 |