| Long name: |
FAIM3 Primary Polyclonal Antibody |
| Also known as: |
FAIM3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FAIM3 |
| Specificity: |
This is a highly specific antibody against FAIM3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/390 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FAIM3 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation, Protects cells from FAS-, Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL, The protein encoded by this May play a role in the immune system processes, Very weak expression detected in spleen, and salivary gland, heart, liver, lung, peripheral blood leukocytes, rather than blocking apoptotic signals downstream, thymus and kidneys, The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death, Tissue specificity: Expressed in lymph nodes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FAIM3_HUMAN, Faim3, Fas apoptotic inhibitory molecule 3, Fc mu receptor, IgM Fc receptor, Immunoglobulin mu Fc receptor, R, Regulator of Fas induced apoptosis, Regulator of Fas-induced apoptosis Toso, TOSO |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAIM3 |
| Short name: |
FAIM3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6) apoptotic inhibitory molecule 3 (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, FAIM3 and IDBG-106292 and ENSG00000162894 and 9214, FAIM3 and IDBG-629197 and ENSBTAG00000019796 and 511564, FCMR and TOSO, Faim3 and IDBG-190537 and ENSMUSG00000042474 and 69169, this GO :0002376 and immune system process and biological process this GO :0005576 and extracellular region and cellular component this GO :0006968 and cellular defense response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, Fas apoptotic inhibitory molecule 3 |
| Identity: |
14315 |
| Gene: |
FCMR |
More about : FCMR |
| Long gene name: |
Fc fragment of IgM receptor |
| Synonyms gene: |
FAIM3 |
| Synonyms gene name: |
Fas apoptotic inhibitory molecule 3 |
| Synonyms: |
TOSO |
| Locus: |
1q32, 1 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF057557 |
| Entrez gene record: |
9214 |
| Pubmed identfication: |
9586636 1563211 25888699 |
| RefSeq identity: |
NM_005449 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036457 |